THE IMMUNE SYSTEM—SOME BASIC CONCEPTS

Basic and translational concepts of immune-mediated glomerular diseases.

Genetically modified immune responses to infections and self-antigens initiate most forms of GN by generating pathogen- and danger-associated molecular patterns that stimulate Toll-like receptors and complement. These innate immune responses activate circulating monocytes and resident glomerular cells to release inflammatory mediators and initiate adaptive, antigen-specific immune responses tha...

Basic Concepts

Motivation Most problems in nature have several (possibly conflicting) objectives to be satisfied. Many of these problems are frequently treated as single-objective optimization problems by transforming all but one objective into constraints. What is a multiobjective optimization problem? The Multiobjective Optimization Problem (MOP) (also called multicriteria optimization, multiperformance or ...

Complex concepts into basic concepts

Complex Concepts into Basic Concepts Rick Szostak University of Alberta Tory Building, Edmonton, AB, T6G 2H4, Canada [email protected] 780-492-7645; FAX 780-492-3300 ABSTRACT Interdisciplinary communication, and thus the rate of progress in scholarly understanding, would be greatly enhanced if scholars had access to a universal classification of documents or ideas not grounded in particu...

Mechanism Design: Basic Concepts

The setup is similar to that of a Bayesian game. The ingredients are: 1. denote a typical type of player i. (q (m) , t (m)). All of these are to be chosen by the mechanism designer. We call the pair Γ = (M, φ) a mechanism. We will consider dominant strategy equilibria in these Bayesian games as well as Bayesian Nash equilibria. Whichever solution concept we adopt, we call φ (m) = (q (m) , t (m)...

Basic Theoretical Concepts